Specific Inhibition of Complement Activation Significantly Ameliorates Autoimmune Blistering Disease in Mice

Epidermolysis bullosa acquisita (EBA) is an antibody-mediated blistering skin disease associated with tissue-bound and circulating autoantibodies to type VII collagen (COL7). Transfer of antibodies against COL7 into mice results in a subepidermal blistering phenotype, strictly depending on the compl...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Mihai, Sidonia, Hirose, Misa, Wang, Yi, Thurman, Joshua M., Holers, V. Michael, Morgan, B. Paul, Köhl, Jörg, Zillikens, Detlef, Ludwig, Ralf J., Nimmerjahn, Falk
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865061/
https://ncbi.nlm.nih.gov/pubmed/29616034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00535
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