Ehrlichia chaffeensis TRP120 Effector Targets and Recruits Host Polycomb Group Proteins for Degradation To Promote Intracellular Infection

Ehrlichia chaffeensis has a group of well-characterized type I secreted tandem repeat protein (TRP) effectors that have moonlighting capabilities. TRPs modulate various cellular processes, reprogram host gene transcription as nucleomodulins, function as ubiquitin ligases, and directly activate conse...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Mitra, Shubhajit, Dunphy, Paige S., Das, Seema, Zhu, Bing, Luo, Tian, McBride, Jere W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865042/
https://ncbi.nlm.nih.gov/pubmed/29358333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00845-17
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