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Ehrlichia chaffeensis TRP120 Moonlights as a HECT E3 Ligase Involved in Self- and Host Ubiquitination To Influence Protein Interactions and Stability for Intracellular Survival

Ehrlichia chaffeensis secretes tandem repeat protein (TRP) effectors that are involved in a diverse array of host cell interactions, some of which directly activate cell signaling pathways and reprogram host gene transcription to promote survival in the mononuclear phagocyte. However, the molecular...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Zhu, Bing, Das, Seema, Mitra, Shubhajit, Farris, Tierra R., McBride, Jere W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563569/
https://ncbi.nlm.nih.gov/pubmed/28630068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00290-17
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