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Heterogeneous Cytoskeletal Force Distribution Delineates the Onset Ca(2+) Influx Under Fluid Shear Stress in Astrocytes

Mechanical perturbations increase intracellular Ca(2+) in cells, but the coupling of mechanical forces to the Ca(2+) influx is not well understood. We used a microfluidic chamber driven with a high-speed pressure servo to generate defined fluid shear stress to cultured astrocytes, and simultaneously...

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Vydáno v:Front Cell Neurosci
Hlavní autoři: Maneshi, Mohammad M., Sachs, Frederick, Hua, Susan Z.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864927/
https://ncbi.nlm.nih.gov/pubmed/29615869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00069
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