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Taurine protects dopaminergic neurons in a mouse Parkinson’s disease model through inhibition of microglial M1 polarization

Microglia-mediated neuroinflammation is implicated in multiple neurodegenerative disorders, including Parkinson’s disease (PD). Hence, the modulatioein of sustained microglial activation may have therapeutic potential. This study is designed to test the neuroprotective efficacy of taurine, a major i...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Che, Yuning, Hou, Liyan, Sun, Fuqiang, Zhang, Cong, Liu, Xiaofang, Piao, Fengyuan, Zhang, Dan, Li, Huihua, Wang, Qingshan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864871/
https://ncbi.nlm.nih.gov/pubmed/29568078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0468-2
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