Ataxia-Telangiectasia Mutated Kinase in the Control of Oxidative Stress, Mitochondria, and Autophagy in Cancer: A Maestro With a Large Orchestra

Ataxia-telangiectasia mutated kinase (ATM) plays a central role in the DNA damage response (DDR) and mutations in its gene lead to the development of a rare autosomic genetic disorder, ataxia telangiectasia (A-T) characterized by neurodegeneration, premature aging, defects in the immune response, an...

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Bibliografiske detaljer
Udgivet i:Front Oncol
Main Authors: Stagni, Venturina, Cirotti, Claudia, Barilà, Daniela
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864851/
https://ncbi.nlm.nih.gov/pubmed/29616191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00073
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