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An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations

Protein-protein interactions govern almost all cellular functions. These complex networks of stable and transient associations can be mapped by affinity purification mass spectrometry (AP-MS) and complementary proximity-based labeling methods such as BioID. To exploit the advantages of both strategi...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Liu, Xiaonan, Salokas, Kari, Tamene, Fitsum, Jiu, Yaming, Weldatsadik, Rigbe G., Öhman, Tiina, Varjosalo, Markku
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864832/
https://ncbi.nlm.nih.gov/pubmed/29568061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03523-2
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