Cell-type specific expression of constitutively-active Rheb promotes regeneration of bulbospinal respiratory axons following cervical SCI

Damage to respiratory neural circuitry and consequent loss of diaphragm function is a major cause of morbidity and mortality in individuals suffering from traumatic cervical spinal cord injury (SCI). Repair of CNS axons after SCI remains a therapeutic challenge, despite current efforts. SCI disrupts...

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Pubblicato in:Exp Neurol
Autori principali: Urban, Mark W., Ghosh, Biswarup, Strojny, Laura R., Block, Cole G., Blazejewski, Sara M., Wright, Megan C., Smith, George M., Lepore, Angelo C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864549/
https://ncbi.nlm.nih.gov/pubmed/29453976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2018.02.007
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