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Redox-dependent BMI1 activity drives in vivo adult cardiac progenitor cell differentiation
Accumulation of reactive oxygen species (ROS) is associated with several cardiovascular pathologies and with cell cycle exit by neonanatal cardiomyocytes, a key limiting factor in the regenerative capacity of the adult mammalian heart. The polycomb complex component BMI1 is linked to adult progenito...
Gespeichert in:
| Veröffentlicht in: | Cell Death Differ |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5864208/ https://ncbi.nlm.nih.gov/pubmed/29323265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-017-0022-2 |
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