Redox-dependent BMI1 activity drives in vivo adult cardiac progenitor cell differentiation

Accumulation of reactive oxygen species (ROS) is associated with several cardiovascular pathologies and with cell cycle exit by neonanatal cardiomyocytes, a key limiting factor in the regenerative capacity of the adult mammalian heart. The polycomb complex component BMI1 is linked to adult progenito...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Differ
Prif Awduron: Herrero, Diego, Tomé, María, Cañón, Susana, Cruz, Francisco M., Carmona, Rosa María, Fuster, Encarna, Roche, Enrique, Bernad, Antonio
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864208/
https://ncbi.nlm.nih.gov/pubmed/29323265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-017-0022-2
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