Lataa...
The interplay between mutant p53 and the mevalonate pathway
Missense mutations in the TP53 gene lead to accumulation of dysfunctional TP53 proteins in tumors, showing oncogenic gain-of-function (GOF) activities. Stabilization of mutant TP53 (mutp53) is required for the GOF; however, the mechanisms by which mutp53 promotes cancer progression and how mutp53 st...
Tallennettuna:
| Julkaisussa: | Cell Death Differ |
|---|---|
| Päätekijät: | , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group UK
2017
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5864191/ https://ncbi.nlm.nih.gov/pubmed/29238070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-017-0026-y |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|