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Improving the efficiency of homologous recombination by chemical and biological approaches in Yarrowia lipolytica
Gene targeting is a challenge in Yarrowia lipolytica (Y. lipolytica) where non-homologous end-joining (NHEJ) is predominant over homologous recombination (HR). To improve the frequency and efficiency of HR in Y. lipolytica, the ku70 gene responsible for a double stand break (DSB) repair in the NHEJ...
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| 出版年: | PLoS One |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5864075/ https://ncbi.nlm.nih.gov/pubmed/29566071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194954 |
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