Rats deficient C-type natriuretic peptide suffer from impaired skeletal growth without early death

We have previously investigated the physiological role of C-type natriuretic peptide (CNP) on endochondral bone growth, mainly with mutant mouse models deficient in CNP, and reported that CNP is indispensable for physiological endochondral bone growth in mice. However, the survival rate of CNP knock...

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Pubblicato in:PLoS One
Autori principali: Fujii, Toshihito, Hirota, Keisho, Yasoda, Akihiro, Takizawa, Akiko, Morozumi, Naomi, Nakamura, Ryuichi, Yotsumoto, Takafumi, Kondo, Eri, Yamashita, Yui, Sakane, Yoriko, Kanai, Yugo, Ueda, Yohei, Yamauchi, Ichiro, Yamanaka, Shigeki, Nakao, Kazumasa, Kuwahara, Koichiro, Jindo, Toshimasa, Furuya, Mayumi, Mashimo, Tomoji, Inagaki, Nobuya, Serikawa, Tadao, Nakao, Kazuwa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864047/
https://ncbi.nlm.nih.gov/pubmed/29566041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194812
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