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Early MinION(™) nanopore single-molecule sequencing technology enables the characterization of hepatitis B virus genetic complexity in clinical samples
Until recently, the method of choice to characterize viral diversity consisted in cloning PCR amplicons of full-length viral genomes and Sanger-sequencing of multiple clones. However, this is extremely laborious, time-consuming, and low-throughput. Next generation short-read sequencing appears also...
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| Publicado en: | PLoS One |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5864009/ https://ncbi.nlm.nih.gov/pubmed/29566006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194366 |
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