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Rescue of impaired sociability and anxiety-like behavior in adult cacna1c-deficient mice by pharmacologically targeting eIF2α
CACNA1C, encoding the Ca(v)1.2 subunit of L-type Ca(2+) channels, has emerged as one of the most prominent and highly replicable susceptibility genes for several neuropsychiatric disorders. Ca(v)1.2 channels play a crucial role in calcium-mediated processes involved in brain development and neuronal...
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| Publicado no: | Mol Psychiatry |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5863913/ https://ncbi.nlm.nih.gov/pubmed/28584287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2017.124 |
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