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Simulations Suggest Pharmacological Methods for Rescuing Long-Term Potentiation

Congenital cognitive dysfunctions are frequently due to deficits in molecular pathways that underlie the induction or maintenance of synaptic plasticity. For example, Rubinstein-Taybi syndrome (RTS) is due to a mutation in cbp, encoding the histone acetyltransferase CREB-binding protein (CBP). CBP i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Smolen, Paul, Baxter, Douglas A., Byrne, John H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162763/
https://ncbi.nlm.nih.gov/pubmed/25034337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2014.07.006
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