Integrative genomics identifies new genes associated with severe COPD and emphysema

BACKGROUND: Genome-wide association studies have identified several genetic risk loci for severe chronic obstructive pulmonary disease (COPD) and emphysema. However, these studies do not fully explain disease heritability and in most cases, fail to implicate specific genes. Integrative methods that...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Sakornsakolpat, Phuwanat, Morrow, Jarrett D., Castaldi, Peter J., Hersh, Craig P., Bossé, Yohan, Silverman, Edwin K., Manichaikul, Ani, Cho, Michael H.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5863845/
https://ncbi.nlm.nih.gov/pubmed/29566699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0744-9
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