Overexpression of zinc-α2-glycoprotein suppressed seizures and seizure-related neuroflammation in pentylenetetrazol-kindled rats

BACKGROUND: Zinc-α2-glycoprotein (ZAG) is a 42-kDa protein reported as an anti-inflammatory adipocytokine. Evidences from clinical and experimental studies revealed that brain inflammation plays important roles in epileptogenesis and seizure. Interestingly, closely relationship between ZAG and many...

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Udgivet i:J Neuroinflammation
Main Authors: Liu, Ying, Wang, Teng, Liu, Xi, Wen, Yuetao, Xu, Tao, Yu, Xinyuan, Wei, Xin, Ding, Xueying, Mo, Lijuan, Yin, Maojia, Tan, Xinjie, Chen, Lifen
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5863804/
https://ncbi.nlm.nih.gov/pubmed/29566716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1132-6
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