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Combined effects of epileptic seizure and phenobarbital induced overexpression of P-glycoprotein in brain of chemically kindled rats

BACKGROUND AND PURPOSE: The multidrug resistance of epilepsy may result from the overexpression of P-glycoprotein, but the mechanisms are unclear. We investigated whether the overexpression of P-glycoprotein in the brains of subjects with pharmacoresistant epilepsy resulted from both drug effects an...

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Detaylı Bibliyografya
Asıl Yazarlar: Jing, Xinyue, Liu, Xiang, Wen, Tao, Xie, Shanshan, Yao, Dan, Liu, Xiaodong, Wang, Guangji, Xie, Lin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Publishing Ltd 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850407/
https://ncbi.nlm.nih.gov/pubmed/20233212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00634.x
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