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Reaction products of hexamethylene diisocyanate vapors with “self” molecules in the airways of rabbits exposed via tracheostomy

1. Hexamethylenediisocyanate (HDI) is a widely used aliphatic diisocyanate and a well-recognized cause of occupational asthma. 2. “Self” molecules (peptides/proteins) in the lower airways, susceptible to chemical reactivity with HDI, have been hypothesized to play a role in asthma pathogenesis and/o...

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Dettagli Bibliografici
Pubblicato in:Xenobiotica
Autori principali: Wisnewski, Adam V., Kanyo, Jean, Asher, Jennifer, Goodrich, James A., Barnett, Grace, Patrylak, Lyn, Liu, Jian, Redlich, Carrie A., Nassar, Ala F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5863241/
https://ncbi.nlm.nih.gov/pubmed/28489470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/00498254.2017.1329569
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