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Novel Bivalent 5-HT(2A) Receptor Antagonists Exhibit High Affinity and Potency in Vitro and Efficacy in Vivo
The 5-HT(2A)R plays an important role in various neuropsychiatric disorders including cocaine use disorder and schizophrenia. Homodimerization of this receptor has been suggested but tools that allow direct assessment of 5-HT(2A)R:5-HT(2A)R homodimer relevance in these disorders are necessary. We ch...
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| Publicado en: | ACS Chem Neurosci |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5862780/ https://ncbi.nlm.nih.gov/pubmed/29111677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.7b00309 |
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