RNA-dependent chromatin targeting of TET2 for endogenous retrovirus control in pluripotent stem cells

Ten-eleven translocation (TET) proteins play key roles in regulating the methylation status of DNA through oxidizing methylcytosines (5mC), generating 5-hydroxymethylcytosines (5hmC) that can both serve as stable epigenetic marks and participate in active demethylation. Unlike the other TET-family m...

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Publicado no:Nat Genet
Main Authors: Guallar, Diana, Bi, Xianju, Pardavila, Jose Angel, Huang, Xin, Saenz, Carmen, Shi, Xianle, Zhou, Hongwei, Faiola, Francesco, Ding, Junjun, Haruehanroengra, Phensinee, Yang, Fan, Li, Dan, Sanchez-Priego, Carlos, Saunders, Arven, Pan, Feng, Valdes, Victor Julian, Kelley, Kevin, Blanco, Miguel G., Chen, Lingyi, Wang, Huayan, Sheng, Jia, Xu, Mingjiang, Fidalgo, Miguel, Shen, Xiaohua, Wang, Jianlong
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862756/
https://ncbi.nlm.nih.gov/pubmed/29483655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-018-0060-9
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