The Sin3a/HDAC corepressor complex functionally cooperates with Nanog to promote pluripotency

Although Sin3a is required for survival of early embryos and embryonic stem cells (ESCs), the role of Sin3a in the maintenance and establishment of pluripotency remains unclear. Here we find that the Sin3a/HDAC corepressor complex maintains ESC pluripotency and promotes the generation of induced plu...

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Publicat a:Cell Rep
Autors principals: Saunders, Arven, Huang, Xin, Fidalgo, Miguel, Reimer, Michael H., Faiola, Francesco, Ding, Junjun, Sánchez-Priego, Carlos, Guallar, Diana, Sáenz, Carmen, Li, Dan, Wang, Jianlong
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328122/
https://ncbi.nlm.nih.gov/pubmed/28199843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.01.055
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