Selenoprotein K deficiency inhibits melanoma by reducing calcium flux required for tumor growth and metastasis

Interest has emerged in the therapeutic potential of inhibiting store operated calcium (Ca(2+)) entry (SOCE) for melanoma and other cancers because malignant cells exhibit a strong dependence on Ca(2+) flux for disease progression. We investigated the effects of deleting Selenoprotein K (SELENOK) in...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Marciel, Michael P., Khadka, Vedbar S., Deng, Youpeng, Kilicaslan, Pascal, Pham, Andrew, Bertino, Pietro, Lee, Katie, Chen, Suzie, Glibetic, Natalija, Hoffmann, FuKun W., Matter, Michelle L., Hoffmann, Peter R.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862587/
https://ncbi.nlm.nih.gov/pubmed/29568366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24388
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