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Selenoprotein K knockout mice exhibit deficient calcium flux in immune cells and impaired immune responses

Selenoprotein K (Sel K) is a selenium-containing protein for which no function has been identified. We found that Sel K is an endoplasmic reticulum (ER) transmembrane protein expressed at relatively high levels in immune cells and is regulated by dietary selenium. Sel K(−/−) mice were generated and...

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Detalhes bibliográficos
Main Authors: Verma, Saguna, Hoffmann, FuKun W., Kumar, Mukesh, Huang, Zhi, Roe, Kelsey, Nguyen-Wu, Elizabeth, Hashimoto, Ann S., Hoffmann, Peter R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088479/
https://ncbi.nlm.nih.gov/pubmed/21220695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002878
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