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Laminin signals initiate the reciprocal loop that informs breast-specific gene expression and homeostasis by activating NO, p53 and microRNAs

How mammalian tissues maintain their architecture and tissue-specificity is poorly understood. Previously, we documented both the indispensable role of the extracellular matrix (ECM) protein, laminin-111 (LN1), in the formation of normal breast acini, and the phenotypic reversion of cancer cells to...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Furuta, Saori, Ren, Gang, Mao, Jian-Hua, Bissell, Mina J
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862529/
https://ncbi.nlm.nih.gov/pubmed/29560860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26148
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