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Integrative single-cell omics analyses reveal epigenetic heterogeneity in mouse embryonic stem cells

Embryonic stem cells (ESCs) consist of a population of self-renewing cells displaying extensive phenotypic and functional heterogeneity. Research towards the understanding of the epigenetic mechanisms underlying the heterogeneity among ESCs is still in its initial stage. Key issues, such as how to i...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Luo, Yanting, He, Jianlin, Xu, Xiguang, Sun, Ming-an, Wu, Xiaowei, Lu, Xuemei, Xie, Hehuang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862410/
https://ncbi.nlm.nih.gov/pubmed/29561833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006034
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