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Integrative single-cell omics analyses reveal epigenetic heterogeneity in mouse embryonic stem cells

Embryonic stem cells (ESCs) consist of a population of self-renewing cells displaying extensive phenotypic and functional heterogeneity. Research towards the understanding of the epigenetic mechanisms underlying the heterogeneity among ESCs is still in its initial stage. Key issues, such as how to i...

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Dades bibliogràfiques
Publicat a:PLoS Comput Biol
Autors principals: Luo, Yanting, He, Jianlin, Xu, Xiguang, Sun, Ming-an, Wu, Xiaowei, Lu, Xuemei, Xie, Hehuang
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862410/
https://ncbi.nlm.nih.gov/pubmed/29561833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006034
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