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Integrative single-cell omics analyses reveal epigenetic heterogeneity in mouse embryonic stem cells

Embryonic stem cells (ESCs) consist of a population of self-renewing cells displaying extensive phenotypic and functional heterogeneity. Research towards the understanding of the epigenetic mechanisms underlying the heterogeneity among ESCs is still in its initial stage. Key issues, such as how to i...

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發表在:PLoS Comput Biol
Main Authors: Luo, Yanting, He, Jianlin, Xu, Xiguang, Sun, Ming-an, Wu, Xiaowei, Lu, Xuemei, Xie, Hehuang
格式: Artigo
語言:Inglês
出版: Public Library of Science 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862410/
https://ncbi.nlm.nih.gov/pubmed/29561833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006034
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