Co-localization and Distribution of Cerebral APP and SP1 and its Relationship to Amyloidogenesis

Alzheimer's disease is characterized by amyloid β peptide (Aβ)-loaded plaques in the brain. Aβ is a cleavage fragment of amyloid-β protein precursor (APP) and over production of APP may lead to amyloidogenesis. The regulatory region of APP gene contains consensus sites recognized by transcripti...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Brock, Brian, Basha, Md. Riyaz, DiPalma, Katie, Anderson, Amy, Harry, G. Jean, Rice, Deborah C., Maloney, Bryan., Lahiri, Debomoy K., Zawia, Nasser H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862394/
https://ncbi.nlm.nih.gov/pubmed/18334759
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