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Nickel induces transcriptional down-regulation of DNA repair pathways in tumorigenic and non-tumorigenic lung cells

The heavy metal nickel is a known carcinogen, and occupational exposure to nickel compounds has been implicated in human lung and nasal cancers. Unlike many other environmental carcinogens, however, nickel does not directly induce DNA mutagenesis, and the mechanism of nickel-related carcinogenesis r...

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Bibliografische gegevens
Gepubliceerd in:Carcinogenesis
Hoofdauteurs: Scanlon, Susan E, Scanlon, Christine D, Hegan, Denise C, Sulkowski, Parker L, Glazer, Peter M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862357/
https://ncbi.nlm.nih.gov/pubmed/28472268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgx038
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