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Curcumin sensitizes pancreatic cancer cells to gemcitabine by attenuating PRC2 subunit EZH2, and the lncRNA PVT1 expression

Development of resistance to chemotherapeutic drugs is a major challenge in the care of patients with pancreatic ductal adenocarcinoma (PDAC). Acquired resistance to chemotherapeutic agents in PDAC has been linked to a subset of cancer cells termed ‘cancer stem cells’ (CSCs). Therefore, an improved...

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Vydáno v:Carcinogenesis
Hlavní autoři: Yoshida, Kazuhiro, Toden, Shusuke, Ravindranathan, Preethi, Han, Haiyong, Goel, Ajay
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862331/
https://ncbi.nlm.nih.gov/pubmed/29048549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgx065
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