Curcumin sensitizes pancreatic cancer cells to gemcitabine by attenuating PRC2 subunit EZH2, and the lncRNA PVT1 expression

Development of resistance to chemotherapeutic drugs is a major challenge in the care of patients with pancreatic ductal adenocarcinoma (PDAC). Acquired resistance to chemotherapeutic agents in PDAC has been linked to a subset of cancer cells termed ‘cancer stem cells’ (CSCs). Therefore, an improved...

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Bibliografiske detaljer
Udgivet i:Carcinogenesis
Main Authors: Yoshida, Kazuhiro, Toden, Shusuke, Ravindranathan, Preethi, Han, Haiyong, Goel, Ajay
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Cancer Biomarkers and Molecular Epidemiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862331/
https://ncbi.nlm.nih.gov/pubmed/29048549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgx065
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