Transcriptional and post-transcriptional upregulation of p27 mediates growth inhibition of isorhapontigenin (ISO) on human bladder cancer cells

There are few approved drugs available for the treatment of muscle-invasive bladder cancer (MIBC). Recently, we have demonstrated that isorhapontigenin (ISO), a new derivative isolated from the Chinese herb Gnetum cleistostachyum, effectively induces cell-cycle arrest at the G(0)/G(1) phase and inhi...

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Détails bibliographiques
Publié dans:Carcinogenesis
Auteurs principaux: Jiang, Guosong, Huang, Chao, Li, Jingxia, Huang, Haishan, Wang, Jingjing, Li, Yawei, Xie, Fei, Jin, Honglei, Zhu, Junlan, Huang, Chuanshu
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
Sujets:
Carcinogenesis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862297/
https://ncbi.nlm.nih.gov/pubmed/29409027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgy015
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