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IFNΛ3/4 locus polymorphisms and IFNΛ3 circulating levels are associated with COPD severity and outcomes

BACKGROUND: Interferon lambdas (IFNLs) have important anti-viral/bacterial and immunomodulatory functions in the respiratory tract. How do IFNLs impact COPD and its exacerbations? METHODS: Five hundred twenty eight patients were recruited in a prospective observational multicentre cohort (PROMISE) s...

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Bibliografiske detaljer
Udgivet i:BMC Pulm Med
Main Authors: Egli, Adrian, Mandal, Jyotshna, Schumann, Desiree M., Roth, Michael, Thomas, Brad, Lorne Tyrrell, D., Blasi, Francesco, Kostikas, Kostantinos, Boersma, Wim, Milenkovic, Branislava, Lacoma, Alicia, Rentsch, Katharina, Rohde, Gernot G. U., Louis, Renaud, Aerts, Joachim G., Welte, Tobias, Torres, Antoni, Tamm, Michael, Stolz, Daiana
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861655/
https://ncbi.nlm.nih.gov/pubmed/29562888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-018-0616-6
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