IFNΛ3/4 locus polymorphisms and IFNΛ3 circulating levels are associated with COPD severity and outcomes

BACKGROUND: Interferon lambdas (IFNLs) have important anti-viral/bacterial and immunomodulatory functions in the respiratory tract. How do IFNLs impact COPD and its exacerbations? METHODS: Five hundred twenty eight patients were recruited in a prospective observational multicentre cohort (PROMISE) s...

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Detalhes bibliográficos
Publicado no:BMC Pulm Med
Main Authors: Egli, Adrian, Mandal, Jyotshna, Schumann, Desiree M., Roth, Michael, Thomas, Brad, Lorne Tyrrell, D., Blasi, Francesco, Kostikas, Kostantinos, Boersma, Wim, Milenkovic, Branislava, Lacoma, Alicia, Rentsch, Katharina, Rohde, Gernot G. U., Louis, Renaud, Aerts, Joachim G., Welte, Tobias, Torres, Antoni, Tamm, Michael, Stolz, Daiana
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861655/
https://ncbi.nlm.nih.gov/pubmed/29562888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-018-0616-6
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