Impaired Aortic Contractility to Uridine Adenosine Tetraphosphate in Angiotensin II-Induced Hypertensive Mice: Receptor Desensitization?

OBJECTIVE: We previously showed that uridine adenosine tetraphosphate (Up(4)A)-mediated aortic contraction is partly mediated through purinergic P2X(1) receptors (P2X(1)R). It has been reported that the plasma level of Up(4)A is elevated in hypertensive patients, implying a potential role for Up(4)A...

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Bibliographic Details
Published in:Am J Hypertens
Main Authors: Zhou, Zhichao, Yadav, Vishal R., Sun, Changyan, Teng, Bunyen, Mustafa, Jamal S.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861566/
https://ncbi.nlm.nih.gov/pubmed/28034895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ajh/hpw163
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