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APE2 promotes DNA damage response pathway from a single-strand break

As the most common type of DNA damage, DNA single-strand breaks (SSBs) are primarily repaired by the SSB repair mechanism. If not repaired properly or promptly, unrepaired SSBs lead to genome stability and have been implicated in cancer and neurodegenerative diseases. However, it remains unknown how...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Lin, Yunfeng, Bai, Liping, Cupello, Steven, Hossain, Md Akram, Deem, Bradley, McLeod, Melissa, Raj, Jude, Yan, Shan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861430/
https://ncbi.nlm.nih.gov/pubmed/29361157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky020
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