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Single molecule real-time (SMRT) sequencing comes of age: applications and utilities for medical diagnostics
Short read massive parallel sequencing has emerged as a standard diagnostic tool in the medical setting. However, short read technologies have inherent limitations such as GC bias, difficulties mapping to repetitive elements, trouble discriminating paralogous sequences, and difficulties in phasing a...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5861413/ https://ncbi.nlm.nih.gov/pubmed/29401301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky066 |
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