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Redefining the ancestral origins of the interleukin-1 superfamily

The interleukin-1 (IL-1) receptor and ligand families are components of the immune system. Knowledge of their evolutionary history is essential to understand their function. Using chromosomal anatomy and sequence similarity, we show that IL-1 receptor family members are related and nine members are...

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Publicado en:Nat Commun
Main Authors: Rivers-Auty, Jack, Daniels, Michael J. D., Colliver, Isaac, Robertson, David L., Brough, David
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861070/
https://ncbi.nlm.nih.gov/pubmed/29559685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03362-1
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