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The sixth transmembrane segment is a major gating component of the TMEM16A calcium-activated chloride channel
Calcium-activated chloride channels (CaCC) formed by TMEM16A or TMEM16B are broadly expressed in the nervous system, smooth muscles, exocrine glands, and other tissues. With two calcium-binding sites and a pore within each monomer, the dimeric CaCC exhibits voltage dependent calcium sensitivity. Cha...
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| Publicado no: | Neuron |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5860880/ https://ncbi.nlm.nih.gov/pubmed/29478917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.01.048 |
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