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Amino Acid Substitutions of Coiled-Coil Protein Tpr Abrogate Anchorage to the Nuclear Pore Complex but Not Parallel, In-Register Homodimerization

Tpr is a protein component of nuclear pore complex (NPC)-attached intranuclear filaments. Secondary structure predictions suggest a bipartite structure, with a large N-terminal domain dominated by heptad repeats (HRs) typical for coiled-coil–forming proteins. Proposed functions for Tpr have included...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Hase, Manuela E., Kuznetsov, Nikolai V., Cordes, Volker C.
פורמט: Artigo
שפה:Inglês
יצא לאור: The American Society for Cell Biology 2001
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC58605/
https://ncbi.nlm.nih.gov/pubmed/11514627
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