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Adaptive gene- and pathway-trait association testing with GWAS summary statistics

Background: Gene- and pathway-based analyses offer a useful alternative and complement to the usual single SNP-based analysis for GWAS. On the other hand, most existing gene- and pathway-based tests are not highly adaptive, and/or require the availability of individual-level genotype and phenotype d...

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Publicat a:Bioinformatics
Autors principals: Kwak, Il-Youp, Pan, Wei
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860182/
https://ncbi.nlm.nih.gov/pubmed/26656570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv719
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