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Docking-based inverse virtual screening: methods, applications, and challenges

Identifying potential protein targets for a small-compound ligand query is crucial to the process of drug development. However, there are tens of thousands of proteins in human alone, and it is almost impossible to scan all the existing proteins for a query ligand using current experimental methods....

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Bibliografiske detaljer
Udgivet i:Biophys Rep
Main Authors: Xu, Xianjin, Huang, Marshal, Zou, Xiaoqin
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860130/
https://ncbi.nlm.nih.gov/pubmed/29577065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s41048-017-0045-8
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