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Docking-based inverse virtual screening: methods, applications, and challenges

Identifying potential protein targets for a small-compound ligand query is crucial to the process of drug development. However, there are tens of thousands of proteins in human alone, and it is almost impossible to scan all the existing proteins for a query ligand using current experimental methods....

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Detalhes bibliográficos
Publicado no:Biophys Rep
Main Authors: Xu, Xianjin, Huang, Marshal, Zou, Xiaoqin
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860130/
https://ncbi.nlm.nih.gov/pubmed/29577065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s41048-017-0045-8
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