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Dominant Negative c-jun Inhibits Activation of the Cyclin D1 and Cyclin E Kinase Complexes
The AP-1 transcription factor is activated by oncogenic signal transduction cascades and its function is critical for both mitogenesis and carcinogenesis. To define the role of AP-1 in the context of a human fibrosarcoma cell line, HT1080, we expressed a dominant negative c-jun mutant fused to the g...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Cell Biology
2001
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC58599/ https://ncbi.nlm.nih.gov/pubmed/11514621 |
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