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Dominant Negative c-jun Inhibits Activation of the Cyclin D1 and Cyclin E Kinase Complexes

The AP-1 transcription factor is activated by oncogenic signal transduction cascades and its function is critical for both mitogenesis and carcinogenesis. To define the role of AP-1 in the context of a human fibrosarcoma cell line, HT1080, we expressed a dominant negative c-jun mutant fused to the g...

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Publicado en:Mol Biol Cell
Autores principales: Hennigan, Robert F., Stambrook, Peter J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Cell Biology 2001
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC58599/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11514621/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.12.8.2352
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