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Downregulation of MiR-203a Disinhibits Bmi1 and Promotes Growth and Proliferation of Keratinocytes in Cholesteatoma

Background: Keratinocytes are the predominant cell type in a cholesteatoma, and microRNA (miR)-203a has been shown to be essential for the growth and differentiation of keratinocytes. The regulatory mechanisms of miR-203a and Bmi1—the predicted target of miR-203a that is associated with cholesteatom...

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Pubblicato in:Int J Med Sci
Autori principali: Zang, Jian, Hui, Lian, Yang, Ning, Yang, Bo, Jiang, Xuejun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859767/
https://ncbi.nlm.nih.gov/pubmed/29559833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.22410
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