Bushenhuoxue formula attenuates cartilage degeneration in an osteoarthritic mouse model through TGF-β/MMP13 signaling

BACKGROUND: Articular cartilage degeneration plays a key role in the pathogenesis of osteoarthritis (OA). Bushenhuoxue formula (BSHXF) has been widely used in the treatment of OA in clinics. However, the molecular mechanisms responsible for the chondroprotective effect of BSHXF remain to be elucidat...

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Publicat a:J Transl Med
Autors principals: Wang, Ping-er, Zhang, Lei, Ying, Jun, Jin, Xing, Luo, Cheng, Xu, Shibing, Dong, Rui, Xiao, Luwei, Tong, Peijian, Jin, Hongting
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859632/
https://ncbi.nlm.nih.gov/pubmed/29554973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1437-3
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