Bushenhuoxue formula attenuates cartilage degeneration in an osteoarthritic mouse model through TGF-β/MMP13 signaling

BACKGROUND: Articular cartilage degeneration plays a key role in the pathogenesis of osteoarthritis (OA). Bushenhuoxue formula (BSHXF) has been widely used in the treatment of OA in clinics. However, the molecular mechanisms responsible for the chondroprotective effect of BSHXF remain to be elucidat...

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Vydáno v:J Transl Med
Hlavní autoři: Wang, Ping-er, Zhang, Lei, Ying, Jun, Jin, Xing, Luo, Cheng, Xu, Shibing, Dong, Rui, Xiao, Luwei, Tong, Peijian, Jin, Hongting
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859632/
https://ncbi.nlm.nih.gov/pubmed/29554973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1437-3
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