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Pharmacological inhibition of AKT activity in human CD34(+) cells enhances their ability to engraft immunodeficient mice
Although practiced clinically for more than 40 years, the use of hematopoietic stem cell (HSC) transplantation remains limited by the inability to expand functional HSCs ex vivo. To determine the role of phosphoinositide 3-kinase (PI3K)/AKT signaling in human hematopoietic stem and progenitor cell (...
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| 出版年: | Exp Hematol |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5859321/ https://ncbi.nlm.nih.gov/pubmed/27645691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2016.09.003 |
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